tuning tips for going on trip...

What kind of carb are you running? Generally, I'd drop jet sizes on a holley 2 to 4 sizes and bump up my timing by two degrees. Problem is, it'll run like crap till you get to 3500+ feet.

When I drive drive down from Denver (5280'), I bring jets up to 4 sizes larger and my Mallory box has a manual switch that takes out 4 degrees of timing. I hope this helps.