All I can tell you is Don Little, who ran 440 Six Packs in NHRA for years, and set records etc, only ran the vacuum setup. That's all I run. That's all Bob Karakashian runs.
Why mess with success?
Buy yourself a brand new set of carbs, so you know some brain surgeon hasn't been "working on them" and screwed them up beyond repair. Check the M.P. engine book for jetting tips and you'll be fine.