closed chamber vs open chamber edelbrock heads

Hi, I know I started with the question of installing the open chambered edelbrock heads on my 340 with .020 positive deck. But is it possible or practicle to put the closed chamber heads on. I have forged TRW .030 pistons and steel rods. Some people talk about piston to head clearance and quench as the same thing. I have seen where a 440 with 12.1 popup pistons converted from open chamber iron heads to closed chamber edelbrocks. What do you think. Thanks Joe