Two Questions/Old School
I would drive it as is and don't cruise faster than 60mph, I used to run 4.88's and 275/50 BFG's in my driver and I'm about 65-70 miles from the track, with the cam & heads you have humming down the hwy at 4,500 isn't a problem.
As a side note I did switch to 3.91's later and didnt lose any ET but it was harder to hook on radials since I had more wheel speed in 1st.