I personally think its a great idea....I would use a good ole' low compression 318 as the initial foundation (I wouldn't even crack the valve covers/Oil Pan off) and later build a special 360 to shoehorn into the ready to go Turbo System Engine Bay.
At 14.7 psi, a turbo can DOUBLE the Hp/Tq, the same Naturally Aspirated engine made....so figure it like this...300 crank horsepower can be doubled to 600 crank horsepower with boost....its relatively safe...run good fuel and always make sure your Wastegate is dialed in, and I hear of people running big numbers on stock Cast Piston/Crank bottom ends all the time.
I say DO IT!
Good Luck.