True, as if you could put a 500 inch HEMI prostock head/port size on a S/B 425 stroker, you'd have the same thing as the example as above.
Port size shape and volume along with valve size should be taylored to the engine for it's intended purpose. Even though you can get most any head on any engine to work and run so you can drive it, that doesn't mean it'll work best for what it is intended for or be effiecent with fuel or power making.