Suggestions for a 318 build

Not looking to run an overdrive tranny. 400 hp is it a reality in a 318 build? Are we talking stroker? Lots of machining? It's my first engine build so I am not hip to what can be done to a small block. I have to stick to what I have or risk divorce Ha! Ha! It has to be somewhat reliable too. Maybe the most exotic part would be eddy heads and a tunnel ram! I don't really know!