What jet and pv size on a 4150HP on SB?

Check the vacuum with the car at idle in gear with your foot on the brake if you have an auto trans. Note the reading, divide it by two and that will be your correct PV size.

http://www.holley.com/data/TechService/Technical/power_valves.pdf

Holley has a wealth of tuning info on their website:

http://www.holley.com/TechService/Library.asp

Hey ramcharger, i have a manual transmission, and that info you provided from the holley site (thanks btw!) says to check it at idle for a standard transmission, which is how i did it before