I believe it's been done before, they just ran a large enough cam? And isn't the 170 pretty much a zero deck engine? It may be a whole lot easier to achieve zero quench with a 170 than a 225
Zero quench? First, I think you need to read up on the terms you're throwing around. No offense, but you sound like a kid trying to bench race without a bench. Again, no offense. We're trying to help people here. Nothing personal.
Now, by the time you mill the head enough to achieve proper quench (and it AIN'T zero), the head is either going to be so thin it will be unusable, OR you will have hit the water jacket. Sorry, those are just the facts. Can you mill the slant head? Heck yeah and they can stand a LOT of milling, but there isn't enough there to create a quench head. In short, you cannot achieve quench in a slant. It is not a quench engine.
Has 10.5 compression been used with iron heads and no quench on the street with pump gas? You bet. Choosing a camshaft with a late intake valve closing event causes the cylinders to begin building pressure later in the stroke and thereby diminishes cylinder pressure in comparison to a camshaft with an earlier intake closing event.
However, with a slant six, all you have is six cylinders. If you run a camshaft large enough to allow pump gas with an iron head and at 10.5 compression, it will be a dead dog on the street. You will literally need a 3500-4000 converter and 4.30 gears at a minimum and even then it's going to run like stink from idle to 3500.......RIGHT where you want extra kick in a hot street car.
Slants are very peculiar with camshaft selection. It does not take very much to over cam one. Best thing to do is spend your money and mill the head about .100" or so. Get compression up to close to or right at 9:1. Have it professionally ported. Choose a camshaft that will give you the best performance where a real street engine will see the most RPM. Probably in the 1500-5500 range. A nice split pattern cam with around .480-.520 lift and no more than 236* duration @ .050 ground on a 108 or even a 106 LSA. If you go with the 106 LSA, I would keep duration @ .050 to no more than 226 @ .050.
Even so, it will still be somewhat "light switchy" as far as power. If you want a broader torque curve, raise the LSA to 112. That will give it more bottom end and a flatter torque curve at the expense of a little loss on the top end. That's what I would do. You will have better results.
Keeping compression low, will assure it will successfully run on pump gas even in the hottest summer months idling in traffic. Raising compression one whole point only sees an increase in power between 1-3%. With the slant, it's on the low end of that spectrum. Good smart bolt on parts choices such as cam and having the head milled and ported with larger valves installed will net you much more of a power increase than raising the compression too high for pump gas anyway.
Build yours like you want. No need to listen to people who have done it over and over for thirty plus years. That makes too much sense, but this fella needs correct information, not just something repeated from V8 builds that won't work with the slant. Lets try to keep it on track as much as possible.