For the thrid time, if your engine makes it's best power with 36 or 37 or 38 degrees of mechanical advance then that's what you set it for. The vacuum advance will have no impact on that, it only works at part throttle under light cruising conditions. If you were to dyno the engine the vacuum advance will not have any impact on how much power the egine makes because it will never add any timing.
If you get detonation at throttle tip in or under steady state cruise then the vacuum advance is coming in to much to soon. There is a allen head screw down inside the vacuum pod that is accessable via the port on the pod. Adjusting this either increases or decreases the preload on the spring inside the unit. This will adjust the amount of vacuum needed to start adding vacuum advance and the amount of vacuum necessary for all the advance (a number is stamped on the unit telling your the amount of advance, double this number for crank degrees). The other thing to check is to make sure the advance returns quickly when released, you do not want it hanging up.
You should get a vacuum gauge and characterise what the manifold vacuum is under different driving conditions then get a mighty-vac and characterise the advance unit. Then you can start to make educated adjustments to optimze the settings.
BTW, you should not be needing to mix 93 and 110 gas on a "moderately" built 440, seems like you may have too much compression to start with.