Big Pharma had been studying, and producing cannibis products before it was criminalized in 1928/29.
The reason there is no US research is because of it's classification (schedule 1 = ******), nobody, with or without a dozen degrees, or the weight of big Pharma were allowed to own/work/research it in the U.S.
GWPharma, a British co.(owned shares for over a decade) brought out Epidiolex, that reduces dozens of epileptic seizures a day in children, to a few events a month.
The Israelis are doing a lotta work also.
There has never been a death directly attributed with ingesting/smoking pot.
Contrary to popular belief, you could eat handfuls of raw pot, with the only result being green poop.
THC needs to be heated to 240* before the " magic" happens .
Decarboxylation -- https://
www.cnbs.org/cannabis-101/cannabis-decarboxylation/)
Below is a link to a great Read on what big Pharma found before 1929, the products, medications that were avail then .
Big Pharma dosed dogs with ever increasing strengths of THC/CBD to establish dosage, efficacy, and toxicity.
NO DOG EVER DIED ! !
CANNABIS TINCTURES AND FLUID-EXTRACTS