In the mid 50's, Chrysler had many different size Hemi's 241, 331, 354, 392. All had rear distributors. The Hemi style heads were more expensive to manufacture, so they phased out the Hemis after 58 and replaced them with the big blocks "B" & "RB" wedge style heads.
However, they did not make as much power per cubic inch than the Hemis (Don Garlits had a good story about that once). Chrysler tried to get more power out of the big blocks in 62 and started the 413 "Max Wedge" with better flowing heads and cross ram intakes. In 63 & 64 the Max Wedge was bored out to 426 CID but still had "big block" style heads.
In 64 Chrysler decided to go for more power and made a new Hemi head and adapted it to the RB big block with different head bolt pattern. You cannot put big block heads on a 426 Hemi or 426 Hemi heads on a big block as they are not interchangeable. Chrysler then stopped developing the Max Wedge or big block program to develop the Hemis. As previously posted Stage V did a Hemi head that would bolt onto a RB block. The 426 Hemi is easy to tell because of the Hemi heads and front distributor. The old 50's Hemis all had rear distributors. Dead giveaway...
And the older 50's style Hemi heads are not interchangeable with the 426 Hemi heads.
The 426 wedge parts will also fit the regular big blocks. The 426 wedge is an RB block and all parts interchange with other RB blocks. The B blocks can interchange heads with the RB blocks as they are all the same bolt pattern. But you still have the issue of B vs RB for parts interchangeability for the big blocks. The B blocks have a 3.375 or 3 3/8 inch stroke, where the RB blocks have a 3.750 or 3 3/4 inch stroke. The 426 Hemi also shares the 3.750 or 3 3/4 inch stroke with the RB engines. You may also interchange a Hemi (Kellog) crank with a big block (say 440) crank, however the 426 hemi crank is stronger and has 8 bolt flex plate. If you buy a used 426 Hemi always verify what crank you are getting, as many guys like to keep the original 426 Hemi crank for themselves and their big blocks and give you the standard 440 (RB) crank with the Hemi. Buyer beware... Obviously the Hemi Kellog crank is much stronger than the regular RB crank. They have the same main and crank journal diameters to make them work in both applications.