Check the simple, cheap EFI fuel setup in my 65 Dart post. I used an external Walbro pump in engine bay (just above K-frame), supplied by a 3/8" line w/ small filter. Outlet has the Wix Corvette filter/reg (56 psi) that many use ($19, O'Reilly's), w/ original 5/16" line return. Each time you change the filter, you get a new regulator. Isn't that neat?
Pump doesn't cavitate. Companies (Holley, etc) that claim the fuel pump must be at rear, below tank level are crazy. Don't they have any engineers on staff? Ran similar for years on my 65 Newport for Holley Pro-jection. Only problem is if the tank gets real low, the sloshing after a hard stop can starve the pump suction, mainly in my Newport with its wide, shallow tank. A-body tanks sort of have a built-in sump.
Those throttle body EFI's are nice since they use common MPFI type injectors, so you can try different sizes. However, they don't give the best fuel distribution as KitCarlson says. That is a mixed bag. When new, and all injectors are matched, you get great distribution with MPFI. However, as they age, clog and vary, you can get worse distribution than with "single point" injection like a carb or TBI. With MPFI, best to remove and bench-test your injectors every 100K miles to insure they match, or maybe use an IR gun on the exhaust pipes after a hard run to see if even. I don't think that hitting the intake valves is that critical. I was at a presentation by a grad student, funded by GM, long ago where they looked at injecting far upstream in the intake runner (more time to vaporize), but it didn't work significantly better so doesn't matter much. My understanding is that in "sequential injection" they try to spray when the intake valve is closed (most of the time) so it vaporizes from the hot surface. Spraying when open flows raw fuel drops in, so slightly worse emissions, but don't quote me.
What has amazed me and many others is how trouble-free electric fuel injectors have proven. When they first came out, companies assumed they would have continual maintenance problems, and there were all sorts of "injector cleaner" products and machines. Today, those products are mostly hype. There were a few problems with the earliest systems and I recall horror stories of $300/injector replacement costs (x8 for V-8 ).