IMO general purpose gears are from 2.94 to 3.55. With 3.21/3.23's being the 'compromise' gears as others have stated.
I currently have 3.21 gears, and I've done quite a few 500+ miles trips with it. Mostly doing 70mph while pegging at 3100 RPM's. Rear wheels are at 25.7 in diameter (275/40R17 tires).
Keeping between 65-70 mph I can usually get about 16 mpg (I've even got over 17 before). 11-12 around town.
The exhaust drone isn't that bad, since I have straight through style mufflers (Magnaflows) with a crossover pipe. (I had chambered style like Flowmasters before, gave me headaches after about 3-4 hours of driving)
I also have an A999 transmission that surely helps with the off-the-line punch. Honestly, sometimes I do wish I had 2.76 or 2.94 gears when doing the long trips.
BUT, funny thing is I'll be installing an 8.75 rear with 3.55 gears soon and a Gearvendors Overdrive. So with 3.55's plus a 0.78 OD, I'll have my 2.76 gears! (2.77 to be exact).
I had cars with 4.11 gears which sure was fun, but whenever I did any freeway driving 60mph and above it got old pretty quick.
@1973dust Not sure if you knew or not, but the A999 is basically a beefed up version of your A904 commonly found in Dodge Diplomats & Plymouth Gran Fury's plus others in the 1980's and also with different 1st & 2nd gears.
A904: 1st=2.45, 2nd=1.45 & 3rd=1.00
A999: 1st=2.74, 2nd=1.54 & 3rd=1.00